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Different mitotic and apoptotic markers were being analyzed from full cell lysates by immunoblotting. The p38 MAPK protein was utilised here to be a loading Manage. C, abrogation of SAC brought on rapid exit from mitosis and inhibited mobile Demise by LY2523355. HeLa cells were being dealt with with twenty five nmol/L LY2523355 for 12 several hours

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